7K8U
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104
Summary for 7K8U
Entry DOI | 10.2210/pdb7k8u/pdb |
EMDB information | 22729 22730 22731 22732 22733 22734 22735 22736 22737 |
Descriptor | Spike glycoprotein, C104 Fab Heavy Chain, C104 Fab Light Chain, ... (5 entities in total) |
Functional Keywords | sars-cov-2, spike glycoprotein, covid-19, monoclonal antibody, neutralizing antibody, protein-immune system complex, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 5 |
Total formula weight | 468705.77 |
Authors | Barnes, C.O.,Malyutin, A.G.,Bjorkman, P.J. (deposition date: 2020-09-27, release date: 2020-10-21, Last modification date: 2021-01-13) |
Primary citation | Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J. SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588:682-687, 2020 Cited by PubMed: 33045718DOI: 10.1038/s41586-020-2852-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report