7K8M

Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102

7K8M の概要

• エントリーDOI: 10.2210/pdb7k8m/pdb
• 分子名称: C102 Fab Heavy Chain, C102 Fab Light Chain, Spike glycoprotein, ... (4 entities in total)
• 機能のキーワード: human neutralizing antibody, sars-cov-2, receptor binding domain, covid-19, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69414.22

構造登録者

Jette, C.A.,Barnes, C.O.,Bjorkman, P.J. (登録日: 2020-09-27, 公開日: 2020-10-21, 最終更新日: 2023-10-18)

• 主引用文献: Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J.; SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.; Nature, 588:682-687, 2020; PubMed: 33045718; DOI: 10.1038/s41586-020-2852-1

実験手法

X-RAY DIFFRACTION (3.2 Å)