7K7T

Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP

Summary for 7K7T

Entry DOI	10.2210/pdb7k7t/pdb
Descriptor	Isoform 3 of MORC family CW-type zinc finger protein 4, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	chromatin, histone h3k4me3, dna interaction, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	105671.51
Authors	Klein, B.J.,Tencer, A.H.,Kutateladze, T.G. (deposition date: 2020-09-24, release date: 2020-11-11, Last modification date: 2023-10-18)
Primary citation	Tencer, A.H.,Cox, K.L.,Wright, G.M.,Zhang, Y.,Petell, C.J.,Klein, B.J.,Strahl, B.D.,Black, J.C.,Poirier, M.G.,Kutateladze, T.G. Molecular mechanism of the MORC4 ATPase activation. Nat Commun, 11:5466-5466, 2020 Cited by PubMed: 33122719 DOI: 10.1038/s41467-020-19278-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.94 Å)

Structure validation