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7K5V

OXA-48 bound by Compound 3.1

Summary for 7K5V
Entry DOI10.2210/pdb7k5v/pdb
DescriptorBeta-lactamase, NAPHTHALENE-2,6-DISULFONIC ACID, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsbeta-lactamase, carbapenemase, beta-lactamase inhibitor, complex, oxacillinase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceKlebsiella pneumoniae
Total number of polymer chains2
Total formula weight57356.18
Authors
Taylor, D.M.,Hu, L.,Prasad, B.V.V.,Palzkill, T. (deposition date: 2020-09-17, release date: 2021-12-01, Last modification date: 2023-11-15)
Primary citationTaylor, D.M.,Anglin, J.,Hu, L.,Wang, L.,Sankaran, B.,Wang, J.,Matzuk, M.M.,Prasad, B.V.V.,Palzkill, T.
Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48.
Acs Infect Dis., 7:3345-3354, 2021
Cited by
PubMed: 34817169
DOI: 10.1021/acsinfecdis.1c00501
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

221051

數據於2024-06-12公開中

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