7K5V
OXA-48 bound by Compound 3.1
Summary for 7K5V
Entry DOI | 10.2210/pdb7k5v/pdb |
Descriptor | Beta-lactamase, NAPHTHALENE-2,6-DISULFONIC ACID, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | beta-lactamase, carbapenemase, beta-lactamase inhibitor, complex, oxacillinase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 57356.18 |
Authors | Taylor, D.M.,Hu, L.,Prasad, B.V.V.,Palzkill, T. (deposition date: 2020-09-17, release date: 2021-12-01, Last modification date: 2023-11-15) |
Primary citation | Taylor, D.M.,Anglin, J.,Hu, L.,Wang, L.,Sankaran, B.,Wang, J.,Matzuk, M.M.,Prasad, B.V.V.,Palzkill, T. Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7:3345-3354, 2021 Cited by PubMed: 34817169DOI: 10.1021/acsinfecdis.1c00501 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)