7K5F

1.90 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor KM-5-50

7K5F の概要

• エントリーDOI: 10.2210/pdb7k5f/pdb
• 分子名称: Ferroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• 機能のキーワード: biofilms, electron transport, iron storage, iron binding, iron mobilization, protein-protein interaction inhibitor, oxidoreductase
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 229210.99

構造登録者

Lovell, S.,Battaile, K.P.,Soldano, A.,Punchi-Hewage, A.,Meraz, K.,Annor-Gyamfi, J.K.,Yao, H.,Bunce, R.A.,Rivera, M. (登録日: 2020-09-16, 公開日: 2020-12-16, 最終更新日: 2023-10-18)

• 主引用文献: Soldano, A.,Yao, H.,Punchi Hewage, A.N.D.,Meraz, K.,Annor-Gyamfi, J.K.,Bunce, R.A.,Battaile, K.P.,Lovell, S.,Rivera, M.; Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells.; Acs Infect Dis., 7:123-140, 2021; PubMed: 33269912; DOI: 10.1021/acsinfecdis.0c00669

実験手法

X-RAY DIFFRACTION (1.95 Å)