7K4P

Crystal structure of Kemp Eliminase HG3

Summary for 7K4P

• Entry DOI: 10.2210/pdb7k4p/pdb
• Descriptor: Endo-1,4-beta-xylanase (2 entities in total)
• Functional Keywords: kemp elimination, directed evolution, hydrolase
• Biological source: Thermoascus aurantiacus
• Total number of polymer chains: 2
• Total formula weight: 66400.70

Authors

Padua, R.A.P.,Otten, R.,Bunzel, A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D. (deposition date: 2020-09-16, release date: 2020-12-02, Last modification date: 2023-10-18)

• Primary citation: Otten, R.,Padua, R.A.P.,Bunzel, H.A.,Nguyen, V.,Pitsawong, W.,Patterson, M.,Sui, S.,Perry, S.L.,Cohen, A.E.,Hilvert, D.,Kern, D.; How directed evolution reshapes the energy landscape in an enzyme to boost catalysis.; Science, 370:1442-1446, 2020; PubMed: 33214289; DOI: 10.1126/science.abd3623

Experimental method

X-RAY DIFFRACTION (1.08 Å)