7K1F
Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM_88558
Summary for 7K1F
Entry DOI | 10.2210/pdb7k1f/pdb |
Descriptor | Insulin-degrading enzyme, ZINC ION, 3,4-difluoro-N-({1-[(2R)-4-(hydroxyamino)-4-oxo-1-(quinolin-7-yl)butan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide, ... (6 entities in total) |
Functional Keywords | hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 231192.06 |
Authors | Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. (deposition date: 2020-09-07, release date: 2021-09-22, Last modification date: 2023-10-18) |
Primary citation | Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 4 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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