7JXB

The crystal structure of 4-(3'-methoxyphenyl)benzoic acid-bound CYP199A4

7JXB の概要

• エントリーDOI: 10.2210/pdb7jxb/pdb
• 分子名称: Cytochrome P450, 3'-methoxy[1,1'-biphenyl]-4-carboxylic acid, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• 機能のキーワード: cytochrome, p450, monooxygenase, heme, oxygen insertion, oxidoreductase
• 由来する生物種: Rhodopseudomonas palustris (strain HaA2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45467.61

構造登録者

Doherty, D.Z.,Bell, S.G.,Bruning, J. (登録日: 2020-08-27, 公開日: 2022-03-09, 最終更新日: 2023-10-25)

• 主引用文献: Coleman, T.,Lee, J.Z.H.,Kirk, A.M.,Doherty, D.Z.,Podgorski, M.N.,Pinidiya, D.K.,Bruning, J.B.,De Voss, J.J.,Krenske, E.H.,Bell, S.G.; Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.; Chemistry, 28:e202201895-e202201895, 2022; PubMed: 36043399; DOI: 10.1002/chem.202201895

実験手法

X-RAY DIFFRACTION (1.655 Å)