7JWG

OspA-Fab 221-7 complex structure

Summary for 7JWG

• Entry DOI: 10.2210/pdb7jwg/pdb
• Descriptor: Antibody 221-7 Fab heavy chain, Antibody 221-7 Fab light chain, Outer surface protein A, ... (4 entities in total)
• Functional Keywords: ospa-fab complex, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 146560.05

Authors

Rudolph, M.J. (deposition date: 2020-08-25, release date: 2021-09-08, Last modification date: 2023-10-18)

• Primary citation: Schiller, Z.A.,Rudolph, M.J.,Toomey, J.R.,Ejemel, M.,LaRochelle, A.,Davis, S.A.,Lambert, H.S.,Kern, A.,Tardo, A.C.,Souders, C.A.,Peterson, E.,Cannon, R.D.,Ganesa, C.,Fazio, F.,Mantis, N.J.,Cavacini, L.A.,Sullivan-Bolyai, J.,Hu, L.T.,Embers, M.E.,Klempner, M.S.,Wang, Y.; Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody.; J.Clin.Invest., 131:-, 2021; PubMed: 33914704; DOI: 10.1172/JCI144843

Experimental method

X-RAY DIFFRACTION (3.05 Å)