7JVB

Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20

Summary for 7JVB

• Entry DOI: 10.2210/pdb7jvb/pdb
• Descriptor: Spike protein S1, Nanobody Nb20, CACODYLATE ION (3 entities in total)
• Functional Keywords: sars-cov-2, covid-19, nanobody, spike protein, receptor-binding domain, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus); More
• Total number of polymer chains: 4
• Total formula weight: 76012.83

Authors

Xiang, Y.,Xiao, Z.,Liu, H.,Sang, Z.,Schneidman-Duhovny, D.,Zhang, C.,Shi, Y. (deposition date: 2020-08-20, release date: 2020-12-02, Last modification date: 2023-10-18)

• Primary citation: Xiang, Y.,Nambulli, S.,Xiao, Z.,Liu, H.,Sang, Z.,Duprex, W.P.,Schneidman-Duhovny, D.,Zhang, C.,Shi, Y.; Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2.; Science, 370:1479-1484, 2020; PubMed: 33154108; DOI: 10.1126/science.abe4747

Experimental method

X-RAY DIFFRACTION (3.287 Å)