7JQU

Abeta 16-36 beta-hairpin mimic with E22G Arctic mutation

This is a non-PDB format compatible entry.

Summary for 7JQU

• Entry DOI: 10.2210/pdb7jqu/pdb
• Descriptor: Abeta 16-36 beta-hairpin mimic VAL-ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLN-ORN-ALA-ILE-ILE-GLY-LEU-MET (2 entities in total)
• Functional Keywords: alzheimer's disease, amyloid, abeta, oligomer, familial mutant, de novo protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 5379.86

Authors

Kreutzer, A.G.,McKnelly, K.J.,Nowick, J.S. (deposition date: 2020-08-11, release date: 2021-09-08, Last modification date: 2023-10-18)

• Primary citation: McKnelly, K.J.,Kreutzer, A.G.,Howitz, W.J.,Haduong, K.,Yoo, S.,Hart, C.,Nowick, J.S.; Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 .; Biochemistry, 61:446-454, 2022; PubMed: 35213141; DOI: 10.1021/acs.biochem.1c00664

Experimental method

X-RAY DIFFRACTION (2.611 Å)