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7JMW

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab

Summary for 7JMW
Entry DOI10.2210/pdb7jmw/pdb
DescriptorSpike protein S1, COVA1-16 heavy chain, COVA1-16 light chain, ... (4 entities in total)
Functional Keywordssars-cov-2, antibody, spike, coronavirus, covid-19, immune system, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains3
Total formula weight75864.49
Authors
Liu, H.,Yuan, M.,Zhu, X.,Wu, N.C.,Wilson, I.A. (deposition date: 2020-08-03, release date: 2020-10-14, Last modification date: 2023-10-18)
Primary citationLiu, H.,Wu, N.C.,Yuan, M.,Bangaru, S.,Torres, J.L.,Caniels, T.G.,van Schooten, J.,Zhu, X.,Lee, C.D.,Brouwer, P.J.M.,van Gils, M.J.,Sanders, R.W.,Ward, A.B.,Wilson, I.A.
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.
Immunity, 53:1272-1280.e5, 2020
Cited by
PubMed: 33242394
DOI: 10.1016/j.immuni.2020.10.023
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

217705

數據於2024-03-27公開中

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