7JMW
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab
Summary for 7JMW
Entry DOI | 10.2210/pdb7jmw/pdb |
Descriptor | Spike protein S1, COVA1-16 heavy chain, COVA1-16 light chain, ... (4 entities in total) |
Functional Keywords | sars-cov-2, antibody, spike, coronavirus, covid-19, immune system, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 3 |
Total formula weight | 75864.49 |
Authors | Liu, H.,Yuan, M.,Zhu, X.,Wu, N.C.,Wilson, I.A. (deposition date: 2020-08-03, release date: 2020-10-14, Last modification date: 2023-10-18) |
Primary citation | Liu, H.,Wu, N.C.,Yuan, M.,Bangaru, S.,Torres, J.L.,Caniels, T.G.,van Schooten, J.,Zhu, X.,Lee, C.D.,Brouwer, P.J.M.,van Gils, M.J.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53:1272-1280.e5, 2020 Cited by PubMed: 33242394DOI: 10.1016/j.immuni.2020.10.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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