7JMW

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab

7JMW の概要

• エントリーDOI: 10.2210/pdb7jmw/pdb
• 分子名称: Spike protein S1, COVA1-16 heavy chain, COVA1-16 light chain, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, antibody, spike, coronavirus, covid-19, immune system, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 75864.49

構造登録者

Liu, H.,Yuan, M.,Zhu, X.,Wu, N.C.,Wilson, I.A. (登録日: 2020-08-03, 公開日: 2020-10-14, 最終更新日: 2023-10-18)

• 主引用文献: Liu, H.,Wu, N.C.,Yuan, M.,Bangaru, S.,Torres, J.L.,Caniels, T.G.,van Schooten, J.,Zhu, X.,Lee, C.D.,Brouwer, P.J.M.,van Gils, M.J.,Sanders, R.W.,Ward, A.B.,Wilson, I.A.; Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.; Immunity, 53:1272-1280.e5, 2020; PubMed: 33242394; DOI: 10.1016/j.immuni.2020.10.023

実験手法

X-RAY DIFFRACTION (2.89 Å)