7JIR
The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant, in complex with PLP_Snyder457 inhibitor
7JIR の概要
エントリーDOI | 10.2210/pdb7jir/pdb |
関連するPDBエントリー | 6WRH 6WZU |
分子名称 | Papain-like protease, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION, ... (7 entities in total) |
機能のキーワード | covid-19, coronavirus, sars, cov-2, papain-like protease, idp51000, center for structural genomics of infectious diseases, csgid, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 36889.81 |
構造登録者 | Osipiuk, J.,Tesar, C.,Endres, M.,Lisnyak, V.,Maki, S.,Taylor, C.,Zhang, Y.,Zhou, Z.,Azizi, S.A.,Jones, K.,Kathayat, R.,Snyder, S.A.,Dickinson, B.C.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-07-23, 公開日: 2020-08-05, 最終更新日: 2023-10-18) |
主引用文献 | Osipiuk, J.,Azizi, S.A.,Dvorkin, S.,Endres, M.,Jedrzejczak, R.,Jones, K.A.,Kang, S.,Kathayat, R.S.,Kim, Y.,Lisnyak, V.G.,Maki, S.L.,Nicolaescu, V.,Taylor, C.A.,Tesar, C.,Zhang, Y.A.,Zhou, Z.,Randall, G.,Michalska, K.,Snyder, S.A.,Dickinson, B.C.,Joachimiak, A. Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors. Nat Commun, 12:743-743, 2021 Cited by PubMed: 33531496DOI: 10.1038/s41467-021-21060-3 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.09 Å) |
構造検証レポート
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