7IK8

Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the O'Brien group -- Crystal Structure of SARS-CoV-2 NSP3 Macrodomain in complex with POB0222 (Mac1-x10590)

これはPDB形式変換不可エントリーです。

7IK8 の概要

• エントリーDOI: 10.2210/pdb7ik8/pdb
• Group deposition: Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the O'Brien group (G_1002351)
• 分子名称: Papain-like protease nsp3, (2P)-2-(quinolin-7-yl)cyclopent-1-ene-1-carboxylic acid (3 entities in total)
• 機能のキーワード: diamond i04-1, pandda, xchemexplorer, crystallographic fragment screening, sars-cov-2, macrodomain, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18515.04

構造登録者

Aschenbrenner, J.C.,Watt, G.,Marples, P.G.,Shaw, A.,Wang, X.,Schuller, M.,O'Brien, P.,Fearon, D.,von Delft, F. (登録日: 2025-08-04, 公開日: 2025-08-13)

• 主引用文献: Aschenbrenner, J.C.,Watt, G.,Marples, P.G.,Wang, X.,Donald, J.R.,Butler, W.T.W.,Shaw, A.,Schuller, M.,O'Brien, P.,Fearon, D.,von Delft, F.; Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the O'Brien group; To Be Published,

実験手法

X-RAY DIFFRACTION (1.151 Å)