7I7B

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0038260-001 (A71EV2A-x5203)

これはPDB形式変換不可エントリーです。

7I7B の概要

• エントリーDOI: 10.2210/pdb7i7b/pdb
• Group deposition: Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre (G_1002344)
• 分子名称: Protease 2A, (4S)-1-{[5-bromo-2-(methylsulfanyl)phenyl]acetyl}azepane-4-carboxamide, ZINC ION, ... (5 entities in total)
• 機能のキーワード: diamond light source, i04-1, asap, a71 2a, enterovirus, protease, crystallographic fragment screening, pandda, pandda2, xchemexplorer, viral protein
• 由来する生物種: Coxsackievirus A16
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32843.19

構造登録者

Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Kenton, N.,Tucker, J.,DiPoto, M.,Lee, A.,Fearon, D.,von Delft, F. (登録日: 2025-03-12, 公開日: 2025-04-02, 最終更新日: 2025-04-09)

• 主引用文献: Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Kenton, N.,Tucker, J.,DiPoto, M.,Lee, A.,Fearon, D.,von Delft, F.; Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre; To Be Published,

実験手法

X-RAY DIFFRACTION (1.36 Å)