7I2B

Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z68404778 (DNV2_NS5A-x0249)

7I2B の概要

• エントリーDOI: 10.2210/pdb7i2b/pdb
• Group deposition: Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 (G_1002341)
• 分子名称: NS5 RNA-dependent RNA polymerase, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (9 entities in total)
• 機能のキーワード: diamond light source, i04-1, readdi, dengue virus, crystallographic fragment screening, pandda, xchemexplorer, cluster4x, viral protein
• 由来する生物種: dengue virus type 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 75114.37

構造登録者

Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E. (登録日: 2025-03-06, 公開日: 2025-04-02)

• 主引用文献: Aschenbrenner, J.C.,Saini, M.,Chopra, A.,Marples, P.G.,Balcomb, B.H.,Lithgo, R.M.,Fearon, D.,von Delft, F.,Ruiz, F.X.,Arnold, E.; Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2; To Be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)