7HXR

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0035390-001 (A71EV2A-x4310)

これはPDB形式変換不可エントリーです。

7HXR の概要

• エントリーDOI: 10.2210/pdb7hxr/pdb
• Group deposition: Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre (G_1002329)
• 分子名称: Protease 2A, (3S)-N~1~-[2-methoxy-3-(trifluoromethyl)phenyl]piperidine-1,3-dicarboxamide, ZINC ION, ... (5 entities in total)
• 機能のキーワード: diamond light source, i04-1, asap, a71 2a, enterovirus, protease, crystallographic fragment screening, pandda, pandda2, xchemexplorer, viral protein, hydrolase
• 由来する生物種: Coxsackievirus A16
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32841.31

構造登録者

Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Kenton, N.,Tucker, J.,DiPoto, M.,Lee, A.,Fearon, D.,von Delft, F. (登録日: 2025-01-10, 公開日: 2025-02-26)

• 主引用文献: Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Kenton, N.,Tucker, J.,DiPoto, M.,Lee, A.,Fearon, D.,von Delft, F.; Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre; To Be Published,

実験手法

X-RAY DIFFRACTION (1.345 Å)