7HUD

PanDDA analysis group deposition -- Main Protease (SARS-CoV-2) in complex with fragment B08 from the F2X-Entry Screen in monoclinic space group

7HUD の概要

• エントリーDOI: 10.2210/pdb7hud/pdb
• Group deposition: PanDDA analysis group deposition -- Main Protease (SARS-CoV-2) in complex with fragments from the F2X-Entry Screen in monoclinic space group (G_1002326)
• 分子名称: 3C-like proteinase nsp5, ethyl 1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, fragment screen, main protease, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2,2019-nCoV)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34174.03

構造登録者

Barthel, T.,Benz, L.S.,Wollenhaupt, J.,Weiss, M.S. (登録日: 2025-01-07, 公開日: 2025-01-15)

• 主引用文献: Barthel, T.,Wollenhaupt, J.,Benz, L.S.,Reincke, P.,Zhang, L.,Lennartz, F.,Tabermann, H.,Mueller, U.,Meente, A.,Hilgenfeld, R.,Weiss, M.S.; Orthorhombic SARS-CoV-2 main protease crystals provide higher success rate in fragment screening; To be published,

実験手法

X-RAY DIFFRACTION (1.61 Å)