7HOI

Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with POB0140 (A71EV2A-x1247)

Summary for 7HOI

• Entry DOI: 10.2210/pdb7hoi/pdb
• Group deposition: Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease (G_1002323)
• Descriptor: Protease 2A, (3R,4S)-4-(3-methoxyphenyl)oxan-3-amine, ZINC ION, ... (5 entities in total)
• Functional Keywords: diamond light source, i03, asap, coxsackievirus a16, crystallographic fragment screening, pandda, pandda2, xchemexplorer, viral protein
• Biological source: Coxsackievirus A16; More
• Total number of polymer chains: 1
• Total formula weight: 16399.81

Authors

Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Fearon, D.,von Delft, F. (deposition date: 2024-11-06, release date: 2024-12-18)

• Primary citation: Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Fearon, D.,von Delft, F.; Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)