7GQE
PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with Z57473948
7GQE の概要
エントリーDOI | 10.2210/pdb7gqe/pdb |
Group deposition | PanDDA analysis group deposition (G_1002271) |
分子名称 | Protease 3C, N-cyclopropyl-2-hydroxybenzamide, DIMETHYL SULFOXIDE, ... (4 entities in total) |
機能のキーワード | diamond i04-1 fragment screening, pandda, xchemexplorer, xce, viral protease, 3c, viral protein |
由来する生物種 | Human Enterovirus D68 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 40507.35 |
構造登録者 | Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Aschenbrenner, J.C.,Balcomb, B.H.,Godoy, A.S.,Marples, P.G.,Ni, X.,Tomlinson, C.W.E.,Thompson, W.,Wild, C.,Fearon, D.,Walsh, M.A.,von Delft, F. (登録日: 2023-08-24, 公開日: 2023-11-29, 最終更新日: 2024-10-16) |
主引用文献 | Lithgo, R.M.,Tomlinson, C.W.E.,Fairhead, M.,Winokan, M.,Thompson, W.,Wild, C.,Aschenbrenner, J.C.,Balcomb, B.H.,Marples, P.G.,Chandran, A.V.,Golding, M.,Koekemoer, L.,Williams, E.P.,Wang, S.,Ni, X.,MacLean, E.,Giroud, C.,Godoy, A.S.,Xavier, M.A.,Walsh, M.,Fearon, D.,von Delft, F. Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals. Biorxiv, 2024 Cited by PubMed: 38746446DOI: 10.1101/2024.04.29.591684 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.44 Å) |
構造検証レポート
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