7GCH
STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS
Summary for 7GCH
Entry DOI | 10.2210/pdb7gch/pdb |
Descriptor | GAMMA-CHYMOTRYPSIN A, 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), ... (5 entities in total) |
Functional Keywords | hydrolase (serine proteinase) |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00766 P00766 P00766 |
Total number of polymer chains | 3 |
Total formula weight | 25634.94 |
Authors | Brady, K.,Ringe, D.,Abeles, R.H. (deposition date: 1990-04-06, release date: 1990-10-15, Last modification date: 2024-06-05) |
Primary citation | Brady, K.,Wei, A.Z.,Ringe, D.,Abeles, R.H. Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. Biochemistry, 29:7600-7607, 1990 Cited by PubMed: 2271520DOI: 10.1021/bi00485a009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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