7G21

Crystal Structure of human FABP4 in complex with 4-hydroxy-2-[(E)-2-(2-phenylcyclohexyl)ethenyl]-2,3-dihydropyran-6-one, i.e. SMILES [C@H]1([C@@H](/C=C/[C@H]2CC(=CC(=O)O2)O)CCCC1)c1ccccc1 with IC50=0.065 microM

Summary for 7G21

• Entry DOI: 10.2210/pdb7g21/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein, adipocyte, FORMIC ACID, SULFATE ION, ... (6 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15498.09

Authors

Ehler, A.,Benz, J.,Obst, U.,Boehringer, M.,Rudolph, M.G. (deposition date: 2023-05-04, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.12 Å)