7G12
Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-propan-2-yl-3-(1H-tetrazol-5-yl)pyridin-2-amine
Summary for 7G12
Entry DOI | 10.2210/pdb7g12/pdb |
Group deposition | To be published (G_1002264) |
Descriptor | Fatty acid-binding protein, adipocyte, (3M,6P)-N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-(propan-2-yl)-3-(1H-tetrazol-5-yl)pyridin-2-amine, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 15559.01 |
Authors | Ehler, A.,Benz, J.,Obst, U.,Kuhne, H.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-04-03) |
Primary citation | Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G. Crystal Structure of a human FABP4 binding site mutated to that of FABP5 complex To be published, |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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