7G0B

Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid, i.e. SMILES [C@@H]1([C@@H](CCN(c2c1cc(cc2)Br)C)C(=O)O)c1ccccc1 with IC50=2.3 microM

Summary for 7G0B

• Entry DOI: 10.2210/pdb7g0b/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein 5, DIMETHYL SULFOXIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16002.17

Authors

Ehler, A.,Benz, J.,Obst, U.,Ceccarelli-Simona, M.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP5 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)