7FZ9

Crystal Structure of human FABP4 in complex with N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-propan-2-yl-3-(1H-tetrazol-5-yl)pyridin-2-amine, i.e. SMILES c1c(nc(c(c1c1ccccc1)C1=NN=NN1)N(C(C)C)C)C1=C(C=CS1)C with IC50=0.0624135 microM

7FZ9 の概要

• エントリーDOI: 10.2210/pdb7fz9/pdb
• Group deposition: To be published (G_1002264)
• 分子名称: Fatty acid-binding protein, adipocyte, (3M,6P)-N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-(propan-2-yl)-3-(1H-tetrazol-5-yl)pyridin-2-amine, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15586.88

構造登録者

Ehler, A.,Benz, J.,Obst, U.,Kuhne, H.,Rudolph, M.G. (登録日: 2023-04-27, 公開日: 2023-06-14, 最終更新日: 2024-11-20)

• 主引用文献: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

実験手法

X-RAY DIFFRACTION (0.96 Å)