7FYX

Crystal Structure of human FABP4 in complex with 2-[(3-phenylthiophen-2-yl)carbamoyl]cyclopentene-1-carboxylic acid, i.e. SMILES S1C(=C(C=C1)c1ccccc1)NC(=O)C1=C(CCC1)C(=O)O with IC50=0.201 microM

7FYX の概要

• エントリーDOI: 10.2210/pdb7fyx/pdb
• Group deposition: To be published (G_1002264)
• 分子名称: Fatty acid-binding protein, adipocyte, SULFATE ION, 2-{[(4R)-4-phenyl-3,4-dihydro-2H-1lambda~4~-thiophen-5-yl]carbamoyl}cyclopent-1-ene-1-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15435.64

構造登録者

Ehler, A.,Benz, J.,Obst, U.,Ceccarelli-Simona, M.,Rudolph, M.G. (登録日: 2023-04-27, 公開日: 2023-06-14, 最終更新日: 2024-11-20)

• 主引用文献: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP4 complex; To be published,

実験手法

X-RAY DIFFRACTION (1.4 Å)