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7FUJ

Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-2-cyano-N-[4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide

Summary for 7FUJ
Entry DOI10.2210/pdb7fuj/pdb
Group depositionTo be published (G_1002263)
DescriptorCyclic GMP-AMP synthase, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
Functional Keywordsimmune response, transferase, ntase, dna sensor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight44136.03
Authors
Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21)
Primary citationGroebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.
Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.79 Å)
Structure validation

227344

数据于2024-11-13公开中

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