7FUJ
Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-2-cyano-N-[4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide
Summary for 7FUJ
Entry DOI | 10.2210/pdb7fuj/pdb |
Group deposition | To be published (G_1002263) |
Descriptor | Cyclic GMP-AMP synthase, ZINC ION, MAGNESIUM ION, ... (8 entities in total) |
Functional Keywords | immune response, transferase, ntase, dna sensor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 44136.03 |
Authors | Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21) |
Primary citation | Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G. Crystal Structure of a human cyclic GMP-AMP synthase complex To be published, |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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