7FUG

Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

7FUG の概要

• エントリーDOI: 10.2210/pdb7fug/pdb
• Group deposition: To be published (G_1002263)
• 分子名称: Cyclic GMP-AMP synthase, ZINC ION, (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, ... (4 entities in total)
• 機能のキーワード: immune response, transferase, ntase, dna sensor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85832.44

構造登録者

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (登録日: 2023-02-08, 公開日: 2024-02-21)

• 主引用文献: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

実験手法

X-RAY DIFFRACTION (2.106 Å)