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7FTW

Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-2-hydroxy-N-[[3-(1-methylpyrazol-4-yl)phenyl]methyl]benzamide

Summary for 7FTW
Entry DOI10.2210/pdb7ftw/pdb
Group depositionTo be published (G_1002263)
DescriptorCyclic GMP-AMP synthase, ZINC ION, 5-bromo-2-hydroxy-N-{[(3M)-3-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}benzamide, ... (4 entities in total)
Functional Keywordsimmune response, transferase, ntase, dna sensor
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight42856.56
Authors
Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21)
Primary citationGroebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.
Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published,
Experimental method
X-RAY DIFFRACTION (2.208 Å)
Structure validation

227561

数据于2024-11-20公开中

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