7FTP

Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(4-chlorophenyl)-10,11-dimethoxy-7-methyl-2,4,6-triazatricyclo[7.3.1.05,13]trideca-1(12),2,4,7,9(13),10-hexaene

7FTP の概要

• エントリーDOI: 10.2210/pdb7ftp/pdb
• Group deposition: To be published (G_1002263)
• 分子名称: Cyclic GMP-AMP synthase, ZINC ION, 4-(4-chlorophenyl)-7,8-dimethoxy-5-methyl-4H-pyrido[2,3,4-de]quinazoline, ... (4 entities in total)
• 機能のキーワード: immune response, transferase, ntase, dna sensor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42824.12

構造登録者

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Zhang, Z.,Rudolph, M.G. (登録日: 2023-02-08, 公開日: 2024-02-21)

• 主引用文献: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

実験手法

X-RAY DIFFRACTION (2.48 Å)