7FTL

Crystal Structure of human cyclic GMP-AMP synthase in complex with 8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid

7FTL の概要

• エントリーDOI: 10.2210/pdb7ftl/pdb
• Group deposition: To be published (G_1002263)
• 分子名称: Cyclic GMP-AMP synthase, ZINC ION, (2P)-8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: nucleotidyltransferase, cyclic gmp-amp synthase, cgas, dna-binding, activator dna, pattern recognition receptor, innate immune response, viral dna recognition, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42770.02

構造登録者

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Brunner, M.,Rudolph, M.G. (登録日: 2023-02-08, 公開日: 2024-02-21)

• 主引用文献: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

実験手法

X-RAY DIFFRACTION (2.2 Å)