7FQK
Crystal Structure of human Legumain in complex with (2S)-N-[(3S)-5-amino-1-(1,3-oxazol-2-yl)-5-oxopent-1-yn-3-yl]-1-[1-[4-(trifluoromethoxy)phenyl]cyclopropanecarbonyl]pyrrolidine-2-carboxamide
Summary for 7FQK
Entry DOI | 10.2210/pdb7fqk/pdb |
Group deposition | To be published (G_1002245) |
Descriptor | Legumain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | cysteine protease, allosteric inhibitor, asparaginyl endopeptidase, alzheimer's disease, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 207201.29 |
Authors | Ehler, A.,Benz, J.,Bartels, B.,Rudolph, M.G. (deposition date: 2022-10-05, release date: 2023-10-11, Last modification date: 2023-11-15) |
Primary citation | Bartels, B.,Kuhn, B.,Benz, J.,Rudolph, M.G. Crystal Structure of a human Legumain complex To be published, |
Experimental method |
Structure validation
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