7FQK

Crystal Structure of human Legumain in complex with (2S)-N-[(3S)-5-amino-1-(1,3-oxazol-2-yl)-5-oxopent-1-yn-3-yl]-1-[1-[4-(trifluoromethoxy)phenyl]cyclopropanecarbonyl]pyrrolidine-2-carboxamide

7FQK の概要

• エントリーDOI: 10.2210/pdb7fqk/pdb
• Group deposition: To be published (G_1002245)
• 分子名称: Legumain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (7 entities in total)
• 機能のキーワード: cysteine protease, allosteric inhibitor, asparaginyl endopeptidase, alzheimer's disease, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 207201.29

構造登録者

Ehler, A.,Benz, J.,Bartels, B.,Rudolph, M.G. (登録日: 2022-10-05, 公開日: 2023-10-11, 最終更新日: 2023-11-15)

• 主引用文献: Bartels, B.,Kuhn, B.,Benz, J.,Rudolph, M.G.; Crystal Structure of a human Legumain complex; To be published,

実験手法