7FIH

luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex

7FIH の概要

• エントリーDOI: 10.2210/pdb7fih/pdb
• EMDBエントリー: 31597
• 分子名称: Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: glycoprotein hormone receptor, chorionic gonadotropin, gpcr, gs-protein, membrane protein
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 198240.05

構造登録者

Duan, J.,Xu, P.,Cheng, X.,Mao, C.,Croll, T.,He, X.,Shi, J.,Luan, X.,Yin, W.,You, E.,Liu, Q.,Zhang, S.,Jiang, H.,Zhang, Y.,Jiang, Y.,Xu, H.E. (登録日: 2021-07-31, 公開日: 2021-09-29, 最終更新日: 2022-02-16)

• 主引用文献: Duan, J.,Xu, P.,Cheng, X.,Mao, C.,Croll, T.,He, X.,Shi, J.,Luan, X.,Yin, W.,You, E.,Liu, Q.,Zhang, S.,Jiang, H.,Zhang, Y.,Jiang, Y.,Xu, H.E.; Structures of full-length glycoprotein hormone receptor signalling complexes.; Nature, 598:688-692, 2021; PubMed: 34552239; DOI: 10.1038/s41586-021-03924-2

実験手法

ELECTRON MICROSCOPY (3.2 Å)