7FH8

Friedel-Crafts alkylation enzyme CylK mutant H391A

Summary for 7FH8

• Entry DOI: 10.2210/pdb7fh8/pdb
• Descriptor: CylK, 2-[(5S,10S)-11-[3,5-bis(oxidanyl)phenyl]-10-methyl-undecan-5-yl]-5-[(2S,7R)-7-fluoranyl-2-methyl-undecyl]benzene-1,3-diol, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: cylindrocyclophane, biosynthesis, beta-propeller, calcium-binding, friedel-crafts alkylation, biosynthetic protein
• Biological source: Cylindrospermum licheniforme UTEX B 2014
• Total number of polymer chains: 1
• Total formula weight: 74978.28

Authors

Wang, H.Q.,Wei, Z.,Xiang, Z. (deposition date: 2021-07-29, release date: 2022-02-16, Last modification date: 2023-11-29)

• Primary citation: Wang, H.Q.,Mou, S.B.,Xiao, W.,Zhou, H.,Hou, X.D.,Wang, S.J.,Wang, Q.,Gao, J.,Wei, Z.,Liu, L.,Xiang, Z.; Structural Basis for the Friedel-Crafts Alkylation in Cylindrocyclophane Biosynthesis; ACS Catal., 12:2108-2117, 2022; DOI: 10.1021/acscatal.1c04816

Experimental method

X-RAY DIFFRACTION (1.32 Å)