7FDW

Crystal structure of pepsin cleaved lactoferrin C-lobe at 2.28 A resolution

Summary for 7FDW

Entry DOI	10.2210/pdb7fdw/pdb
Descriptor	Lactotransferrin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, ... (6 entities in total)
Functional Keywords	c lobe of lactoferrin, hydrolase
Biological source	Bos taurus (Bovine)
Total number of polymer chains	2
Total formula weight	78457.65
Authors	Singh, P.K.,Singh, J.,Maurya, A.,Sharma, P.,Sharma, S.,Singh, T.P. (deposition date: 2021-07-18, release date: 2021-08-04, Last modification date: 2023-11-29)
Primary citation	Singh, J.,Maurya, A.,Singh, P.K.,Viswanathan, V.,Ahmad, M.I.,Sharma, P.,Sharma, S.,Singh, T.P. A Peptide Bond from the Inter-lobe Segment in the Bilobal Lactoferrin Acts as a Preferred Site for Cleavage for Serine Proteases to Generate the Perfect C-lobe: Structure of the Pepsin Hydrolyzed Lactoferrin C-lobe at 2.28 angstrom Resolution. Protein J., 40:857-866, 2021 Cited by PubMed: 34734372 DOI: 10.1007/s10930-021-10028-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.277 Å)

Structure validation