7FB6

C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1)

Summary for 7FB6

• Entry DOI: 10.2210/pdb7fb6/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, COPPER (II) ION, ... (5 entities in total)
• Functional Keywords: superoxide, oxidation, metalloprotein, hydrogen peroxide, filament, als, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 33786.28

Authors

Baek, Y.,Ha, N.-C. (deposition date: 2021-07-08, release date: 2022-10-12, Last modification date: 2023-11-29)

• Primary citation: Baek, Y.,Woo, T.G.,Ahn, J.,Lee, D.,Kwon, Y.,Park, B.J.,Ha, N.C.; Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.; Commun Biol, 5:1085-1085, 2022; PubMed: 36224351; DOI: 10.1038/s42003-022-04017-0

Experimental method

X-RAY DIFFRACTION (1.8 Å)