7F5O
Crystal structure of PTPN2 catalytic domain
Summary for 7F5O
| Entry DOI | 10.2210/pdb7f5o/pdb |
| Descriptor | Tyrosine-protein phosphatase non-receptor type 2, IODIDE ION (3 entities in total) |
| Functional Keywords | protein tyrosine phosphatase, tcptp, ptpn2, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 107213.98 |
| Authors | Singh, J.P.,Lin, M.-J.,Hsu, S.-F.,Lee, C.-C.,Meng, T.-C. (deposition date: 2021-06-22, release date: 2021-12-29, Last modification date: 2023-11-29) |
| Primary citation | Singh, J.P.,Lin, M.J.,Hsu, S.F.,Peti, W.,Lee, C.C.,Meng, T.C. Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix alpha 7 in Phosphatase Activity. Biochemistry, 60:3856-3867, 2021 Cited by PubMed: 34910875DOI: 10.1021/acs.biochem.1c00519 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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