7F51

Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose

7F51 の概要

• エントリーDOI: 10.2210/pdb7f51/pdb
• 分子名称: NAD-dependent protein deacetylase HST2, ZINC ION, [(2R,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] benzoate, ... (4 entities in total)
• 機能のキーワード: histone modification, histone benzoylation, protein-protein interaction, nad-dependent histone deacetylase, nuclear protein
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33252.12

構造登録者

Wang, D.,Yan, F.,Chen, Y. (登録日: 2021-06-21, 公開日: 2022-03-16, 最終更新日: 2023-11-29)

• 主引用文献: Wang, D.,Yan, F.,Wu, P.,Ge, K.,Li, M.,Li, T.,Gao, Y.,Peng, C.,Chen, Y.; Global profiling of regulatory elements in the histone benzoylation pathway.; Nat Commun, 13:1369-1369, 2022; PubMed: 35296687; DOI: 10.1038/s41467-022-29057-2

実験手法

X-RAY DIFFRACTION (1.98 Å)