7F40

Lysophospholipid acyltransferase LPCAT3 in a complex with Arachidonoyl-CoA

7F40 の概要

• エントリーDOI: 10.2210/pdb7f40/pdb
• EMDBエントリー: 31443
• 分子名称: LPCAT3, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
• 機能のキーワード: lysophospholipid acyltransferase, lpcat3, membrane-bound o-acyltransferase, cryo-em, transferase
• 由来する生物種: Gallus gallus (Chicken)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 118212.35

構造登録者

Zhang, Q.,Yao, D.,Rao, B.,Li, S.,Jian, L.,Chen, Y.,Hu, K.,Xia, Y.,Shen, Y.,Cao, Y. (登録日: 2021-06-17, 公開日: 2021-12-01, 最終更新日: 2021-12-15)

• 主引用文献: Zhang, Q.,Yao, D.,Rao, B.,Jian, L.,Chen, Y.,Hu, K.,Xia, Y.,Li, S.,Shen, Y.,Qin, A.,Zhao, J.,Zhou, L.,Lei, M.,Jiang, X.C.,Cao, Y.; The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.; Nat Commun, 12:6869-6869, 2021; PubMed: 34824256; DOI: 10.1038/s41467-021-27244-1

実験手法

ELECTRON MICROSCOPY (3.49 Å)