7F35

Crystal structure of anti S-gatifloxacin antibody Fab fragment in complex with S-gatifloxacin

7F35 の概要

• エントリーDOI: 10.2210/pdb7f35/pdb
• 関連するPDBエントリー: 7F2S
• 分子名称: Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... (10 entities in total)
• 機能のキーワード: antibody, gatifloxacin, fab fragment, enantioselectivity, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 145696.50

構造登録者

Wang, L.T.,Jiao, W.Y.,Shen, X.,Lei, H.T. (登録日: 2021-06-15, 公開日: 2021-12-29, 最終更新日: 2023-11-29)

• 主引用文献: Wang, L.T.,Xie, W.,Jiao, W.Y.,Zhang, C.,Li, X.,Xu, Z.,Huang, X.,Lei, H.T.,Shen, X.; Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin; Rsc Adv, 11:39534-39544, 2021; DOI: 10.1039/D1RA07143B

実験手法

X-RAY DIFFRACTION (2.6 Å)