7ETT

The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV

Summary for 7ETT

• Entry DOI: 10.2210/pdb7ett/pdb
• Descriptor: peptide-inhibitor hit, Peptidyl-prolyl cis-trans isomerase FKBP5 (3 entities in total)
• Functional Keywords: isomerase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 14662.81

Authors

Han, J.T.,Zhu, Y.C.,Pan, D.B.,Xue, H.X.,Wang, S.,Liu, H.X.,He, Y.X.,Yao, X.J. (deposition date: 2021-05-14, release date: 2022-02-23, Last modification date: 2023-11-29)

• Primary citation: Han, J.T.,Zhu, Y.,Pan, D.B.,Xue, H.X.,Wang, S.,Peng, Y.,Liu, H.,He, Y.X.,Yao, X.; Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.; Comput Struct Biotechnol J, 19:4079-4091, 2021; PubMed: 34401048; DOI: 10.1016/j.csbj.2021.07.015

Experimental method

X-RAY DIFFRACTION (1.5 Å)