7ELA
Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A)
Summary for 7ELA
Entry DOI | 10.2210/pdb7ela/pdb |
EMDB information | 31178 |
Descriptor | RING finger protein Z, 3-'vRNA promoter, RNA-directed RNA polymerase L, ... (5 entities in total) |
Functional Keywords | lassa virus, polymerase, z protein, replication regulation, viral protein-rna complex, viral protein/rna |
Biological source | Lassa mammarenavirus More |
Total number of polymer chains | 3 |
Total formula weight | 270426.60 |
Authors | |
Primary citation | Xu, X.,Peng, R.,Peng, Q.,Wang, M.,Xu, Y.,Liu, S.,Tian, X.,Deng, H.,Tong, Y.,Hu, X.,Zhong, J.,Wang, P.,Qi, J.,Gao, G.F.,Shi, Y. Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6:921-931, 2021 Cited by PubMed: 34127846DOI: 10.1038/s41564-021-00916-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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