7EJH

Crystal structure of KRED mutant-F147L/L153Q/Y190P/L199A/M205F/M206F and 2-hydroxyisoindoline-1,3-dione complex

Summary for 7EJH

• Entry DOI: 10.2210/pdb7ejh/pdb
• Descriptor: 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: ketoreductases, nadph-dependent, enantioselectivity, oxidoreductase
• Biological source: Lactobacillus kefiri
• Total number of polymer chains: 4
• Total formula weight: 110791.71

Authors

Cui, J.,Huang, X.,Wang, B.,Zhao, H.,Zhou, J. (deposition date: 2021-04-02, release date: 2022-05-11, Last modification date: 2023-11-29)

• Primary citation: Huang, X.,Feng, J.,Cui, J.,Jiang, G.,Harrison, W.,Zang, X.,Zhou, J.,Wang, B.,Zhao, H.; Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition; Nat Catal, 2022; DOI: 10.1038/s41929-022-00777-4

Experimental method

X-RAY DIFFRACTION (1.72883927603 Å)