7E9I

Crystal structure of a class I PreQ1 riboswitch aptamer (wild-type) complexed with a cognate ligand-derived photoaffinity probe

Summary for 7E9I

Entry DOI	10.2210/pdb7e9i/pdb
Descriptor	33-mer RNA, 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, SULFATE ION, ... (4 entities in total)
Functional Keywords	preq1 riboswitch, cognate ligand-derived photoaffinity probe, rna
Biological source	Caldanaerobacter subterraneus subsp. tengcongensis
Total number of polymer chains	1
Total formula weight	10994.81
Authors	Numata, T.,Schneekloth, J.S. (deposition date: 2021-03-04, release date: 2021-11-17, Last modification date: 2023-11-29)
Primary citation	Balaratnam, S.,Rhodes, C.,Bume, D.D.,Connelly, C.,Lai, C.C.,Kelley, J.A.,Yazdani, K.,Homan, P.J.,Incarnato, D.,Numata, T.,Schneekloth Jr., J.S. A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites. Nat Commun, 12:5856-5856, 2021 Cited by PubMed: 34615874 DOI: 10.1038/s41467-021-25973-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation