7E9E

Crystal structure of a class I PreQ1 riboswitch aptamer (ab13-14) complexed with a cognate ligand-derived photoaffinity probe

7E9E の概要

• エントリーDOI: 10.2210/pdb7e9e/pdb
• 分子名称: 33-mer RNA, 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: preq1 riboswitch, cognate ligand-derived photoaffinity probe, rna
• 由来する生物種: Caldanaerobacter subterraneus subsp. tengcongensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10897.57

構造登録者

Numata, T.,Schneekloth, J.S. (登録日: 2021-03-04, 公開日: 2021-11-17, 最終更新日: 2023-11-29)

• 主引用文献: Balaratnam, S.,Rhodes, C.,Bume, D.D.,Connelly, C.,Lai, C.C.,Kelley, J.A.,Yazdani, K.,Homan, P.J.,Incarnato, D.,Numata, T.,Schneekloth Jr., J.S.; A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites.; Nat Commun, 12:5856-5856, 2021; PubMed: 34615874; DOI: 10.1038/s41467-021-25973-x

実験手法

X-RAY DIFFRACTION (1.57 Å)