7E3D

Crystal structure of human acetylcholinesterase

7E3D の概要

• エントリーDOI: 10.2210/pdb7e3d/pdb
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... (4 entities in total)
• 機能のキーワード: human acetylcholinesterase, hache, alzheimer's disease, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 119977.25

構造登録者

Dileep, K.V.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y.J. (登録日: 2021-02-08, 公開日: 2022-02-16, 最終更新日: 2023-11-29)

• 主引用文献: Dileep, K.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y.; Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery; Int.J.Biol.Macromol., 210:172-181, 2022; DOI: 10.1016/j.ijbiomac.2022.05.009

実験手法

X-RAY DIFFRACTION (2.5 Å)